Cervical Cancer: Symptoms, Causes, Treatment
What are the symptoms of cervical cancer?
Cervical cancer may not cause any symptoms in its early stages. As the cancer progresses, symptoms may develop. Common symptoms of cervical cancer can include:
- Abnormal vaginal bleeding: This can include bleeding between periods, after sexual intercourse, or after menopause.
- Unusual vaginal discharge: The discharge may be watery, bloody, or have a foul odor.
- Pelvic pain: This can occur during or after sexual intercourse or between periods.
- Pain during urination: This can be a symptom if the cancer has spread to nearby tissues.
- Pain in the pelvis or lower back: This can occur if the cancer has spread to nearby tissues or organs.
- Weight loss: This can occur in advanced stages of cervical cancer.
- Fatigue: This can occur as a result of the cancer or due to other symptoms such as pain or bleeding.
It’s important to note that these symptoms can also be caused by other conditions, so it’s essential to consult a healthcare provider for an accurate diagnosis if you experience any of these symptoms. Regular screenings, such as Pap smears and HPV tests, are crucial for detecting cervical cancer early when it is most treatable.
What are the causes of cervical cancer?
Cervical cancer is primarily caused by persistent infection with high-risk types of human papillomavirus (HPV), a common sexually transmitted infection. HPV infection is very common, and most women will be infected with HPV at some point in their lives. However, in most cases, the immune system clears the virus without any problems.
Factors that can increase the risk of developing cervical cancer include:
- HPV infection: Persistent infection with high-risk types of HPV, especially HPV types 16 and 18, is the most significant risk factor for cervical cancer. HPV is passed through genital contact, including sexual contact.
- Smoking: Smoking tobacco increases the risk of cervical cancer. Chemicals from tobacco can damage cervical cells and make them more susceptible to HPV infection.
- Weakened immune system: A weakened immune system due to conditions such as HIV/AIDS or immunosuppressive therapy increases the risk of cervical cancer.
- Chlamydia infection: Infection with the bacterium Chlamydia trachomatis has been linked to an increased risk of cervical cancer.
- Long-term use of oral contraceptives: Women who have used oral contraceptives for five or more years may have a slightly increased risk of cervical cancer compared to non-users.
- Having multiple sexual partners: Having multiple sexual partners or having sexual partners who have had multiple partners increases the risk of HPV infection.
- Early sexual activity: Women who become sexually active at an early age have a higher risk of HPV infection and cervical cancer.
- Family history: Having a mother or sister who has had cervical cancer may increase the risk, possibly due to shared genetic factors or environmental influences.
It’s important to note that most women with HPV do not develop cervical cancer. Vaccination against HPV and regular cervical cancer screening (Pap smears and HPV tests) are important for preventing and detecting cervical cancer early when it is most treatable.
What is the treatment for cervical cancer?
The treatment for cervical cancer depends on several factors, including the stage of the cancer, the patient’s overall health, and their personal preferences. Treatment options may include:
- Surgery: Surgery may be used to remove the cancerous tissue. The type of surgery depends on the stage of the cancer and may include procedures such as a hysterectomy (removal of the uterus) or a trachelectomy (removal of the cervix).
- Radiation therapy: Radiation therapy uses high-energy rays to kill cancer cells. It can be used alone or in combination with surgery or chemotherapy. External beam radiation therapy and brachytherapy (internal radiation therapy) are common types of radiation therapy used for cervical cancer.
- Chemotherapy: Chemotherapy uses drugs to kill cancer cells. It can be used alone or in combination with radiation therapy (chemoradiation). Chemotherapy is often used for advanced cervical cancer or after surgery to reduce the risk of recurrence.
- Targeted therapy: Targeted therapy targets specific molecules involved in cancer cell growth and survival. Drugs such as bevacizumab (Avastin) may be used in combination with chemotherapy for advanced cervical cancer.
- Immunotherapy: Immunotherapy uses the body’s immune system to fight cancer. Drugs such as pembrolizumab (Keytruda) may be used for advanced cervical cancer that has not responded to other treatments.
The choice of treatment depends on several factors, including the stage of the cancer, the patient’s overall health, and their personal preferences. A multidisciplinary team of healthcare providers, including oncologists, surgeons, radiation oncologists, and other specialists, will work together to develop an individualized treatment plan for each patient. Early detection through regular screening (Pap smears and HPV tests) is key to improving the chances of successful treatment for cervical cancer.
What is the cervical cancer survival rate?
The survival rate for cervical cancer varies depending on the stage at which it is diagnosed and other factors. The survival rates are often reported as the percentage of people who survive for a specific period after diagnosis.
According to the American Cancer Society, the 5-year relative survival rate for cervical cancer is as follows:
- Localized (cancer is only in the cervix): About 92%
- Regional (cancer has spread to nearby lymph nodes or tissues): About 57%
- Distant (cancer has spread to distant organs or lymph nodes): About 17%
- All stages combined: About 66%
It’s important to note that survival rates are estimates and can vary based on individual factors such as age, overall health, and response to treatment. Early detection through regular screening (Pap smears and HPV tests) can significantly improve the chances of successful treatment and a better prognosis for cervical cancer.