Urethral Cancer: Symptoms, Causes & Treatment
What are the symptoms of urethral cancer?
Urethral cancer is a rare type of cancer that occurs in the urethra, the tube that carries urine from the bladder to the outside of the body. Symptoms of urethral cancer can vary depending on the location and size of the tumor. Some common symptoms include:
- Blood in the urine (hematuria)
- Pain or burning during urination
- Frequent urination
- Urgency to urinate
- Discharge from the urethra
- A lump or swelling near the urethral opening
- In men, difficulty or pain during ejaculation
- In women, a mass or growth in the vagina
- In advanced cases, pain in the pelvis or lower abdomen, weight loss, and fatigue
It’s important to note that these symptoms can also be caused by other, less serious conditions. However, if you experience any of these symptoms, especially if they persist or worsen over time, it’s important to see a healthcare provider for an evaluation. Early detection and treatment can improve the prognosis for urethral cancer.
What are the causes of urethral cancer?
The exact cause of urethral cancer is not well understood, but several factors may increase the risk of developing this rare type of cancer. These risk factors include:
- Age and Gender: Urethral cancer is more common in older adults, particularly those over the age of 60. It is also more common in women than in men.
- Chronic Inflammation: Chronic inflammation of the urethra, often due to conditions such as urethritis or recurrent urinary tract infections (UTIs), may increase the risk of developing urethral cancer.
- Urethral Diverticulum: A urethral diverticulum is a pouch-like bulge in the urethra that can become infected and inflamed. Long-standing diverticula may increase the risk of developing cancer.
- Sexually Transmitted Infections (STIs): Infections with certain sexually transmitted pathogens, such as human papillomavirus (HPV), may increase the risk of developing urethral cancer.
- Chemical Exposure: Exposure to certain chemicals, such as those found in tobacco smoke or certain industrial chemicals, may increase the risk of developing urethral cancer.
- Other Factors: Other factors that may increase the risk of urethral cancer include a history of bladder cancer, urethral stricture (narrowing of the urethra), and radiation therapy to the pelvic area.
It’s important to note that having one or more risk factors does not mean that a person will develop urethral cancer. Conversely, some people who develop urethral cancer may not have any known risk factors. If you have concerns about your risk of developing urethral cancer, it’s best to discuss them with a healthcare provider.
What is the treatment for urethral cancer?
The treatment for urethral cancer depends on several factors, including the stage of the cancer, the location and size of the tumor, and the overall health of the patient. Treatment options may include:
- Surgery: Surgery is often the primary treatment for urethral cancer. The type of surgery depends on the location and size of the tumor. Surgery may involve removing part or all of the urethra (urethrectomy) and nearby lymph nodes.
- Radiation Therapy: Radiation therapy uses high-energy rays to kill cancer cells. It may be used before surgery to shrink the tumor or after surgery to destroy any remaining cancer cells.
- Chemotherapy: Chemotherapy uses drugs to kill cancer cells. It may be used in combination with surgery and/or radiation therapy, especially for more advanced or aggressive cancers.
- Immunotherapy: Immunotherapy is a type of treatment that helps the immune system recognize and attack cancer cells. It may be used in some cases of urethral cancer, particularly for advanced or recurrent cancers.
- Clinical Trials: Clinical trials are research studies that test new treatments or combinations of treatments. Patients with urethral cancer may be eligible to participate in clinical trials to access new and potentially more effective treatments.
The specific treatment plan for urethral cancer is determined by a multidisciplinary team of healthcare providers, including surgeons, oncologists, radiation oncologists, and other specialists. The goal of treatment is to remove or destroy the cancer while preserving as much normal function and anatomy as possible. Treatment may also focus on managing symptoms and improving quality of life.